Tamil Nadu Government Multi-Super-Speciality Hospital is a 400-bed government-owned super-specialty hospital in Chennai, India. It is located at the Omandurar Government Estate on Anna Salai and was opened in February 2014 as a referral hospital, similar to the All India Institute of Medical Sciences (AIIMS) in New Delhi, built at a cost of ₹ 1,431.4 million.

Originally built as Tamil Nadu legislative assembly and secretariat complex in 2010 to house the assembly hall, secretariat and offices of the chief minister and cabinet ministers, the complex was later converted into a super-specialty hospital.